Table 3.
Univariate and Multivariate analysis in TCGA-PDAC cohort.
| Characteristics | Univariate analysis |
Multivariate analysis |
||||||
|---|---|---|---|---|---|---|---|---|
| HR | 95%CI |
P | HR | 95%CI |
P | |||
| Lower | Upper | Lower | Upper | |||||
| Age (≤60 as reference) | ||||||||
| >60 | 1.245 | 0.772 | 2.010 | 0.369 | ||||
| Gender (Male as reference) | ||||||||
| Female | 1.275 | 0.823 | 1.974 | 0.276 | ||||
| Location (Head as reference) | ||||||||
| Body | 0.657 | 0.264 | 1.634 | 0.366 | ||||
| Tail | 1.186 | 0.543 | 2.593 | 0.669 | ||||
| Others | 0.157 | 0.021 | 1.157 | 0.069 | ||||
| Depth (T1 as reference) | ||||||||
| T2 | 3.759 | 0.461 | 30.681 | 0.216 | ||||
| T3 | 5.074 | 0.703 | 36.627 | 0.107 | ||||
| T4 | 2.608 | 0.162 | 41.914 | 0.499 | ||||
| Lymph node status (N0 as reference) | ||||||||
| N1 | 1.893 | 1.094 | 3.274 | 0.022 | 1.861 | 1.076 | 3.218 | 0.026 |
| Metastasis (M0 as reference) | ||||||||
| M1 | 0.959 | 0.230 | 3.998 | 0.954 | ||||
| Mx | 1.007 | 0.647 | 1.569 | 0.974 | ||||
| Pathological grade (Grade 1 as reference) | ||||||||
| Grade 2 | 1.333 | 0.646 | 2.751 | 0.436 | ||||
| Grade 3 | 1.623 | 0.756 | 3.484 | 0.214 | ||||
| Grade 4 | 1.659 | 0.208 | 13.224 | 0.633 | ||||
| m6Ascore (Low as reference) | ||||||||
| High | 2.344 | 1.509 | 3.641 | <0.001 | 2.315 | 1.493 | 3.590 | <0.001 |