Table 2.
Comparing Laboratory Markers and Therapeutics Received of Patients With and Without Barotrauma on Admission, Day 7, and Day 28.
| Laboratory markers and therapeutics | No barotrauma N = 59 | Barotrauma N = 16 | p-value |
|---|---|---|---|
| On Admission: | |||
| Ferritin | 2200 (5600) | 1500 (1200) | 0.62 |
| D-dimer | 3.4 (5.1) | 3.8 (7.0) | 0.82 |
| Intubated | 10% (6) | 13% (2) | 0.68 |
| SOFA | 3 (2-4) | 3.5 (2-4) | 0.58 |
| Ordinal Scale | 4 (4-5) | 4 (4-5) | 0.47 |
| PaO2: FiO2 Ratio | 205 (98) | 167 (90) | 0.19 |
| Received Glucocorticoids? | 25% (15) | 31% (5) | 0.75 |
| Received Remdesivir? | 3% (2) | 6% (1) | 0.52 |
| Received Vasopressors? | 12% (7) | 0% (0) | 0.33 |
| Received Antibiotics? | 93% (55) | 100% (16) | 0.57 |
| Received Therapeutic Anticoagulation? | 12% (7) | 19% (3) | 0.44 |
| Received Hydroxychloroquine? | 15% (9) | 38% (6) | 0.08 |
| Received Convalescent Plasma? | 5% (3) | 0% (0) | 1.00 |
| Received Tocilizumab? | 0% (0) | 0% (0) | |
| Day 7: | |||
| Ferritin | 2200 (6200) | 1300 (1100) | 0.55 |
| D-dimer | 4.7 (5.5) | 6.6 (6.7) | 0.27 |
| Intubated | 36% (21) | 67% (10) | 0.04 |
| SOFA | 3 (2-4) | 4 (2-4) | 0.86 |
| Ordinal Scale | 5 (4-6) | 6 (5-6) | 0.12 |
| Received Glucocorticoids? | 63% (37) | 69% (11) | 0.77 |
| Received Remdesivir? | 10% (6) | 13% (2) | 0.68 |
| Received Vasopressors? | 27% (16) | 44% (7) | 0.23 |
| Received Antibiotics? | 88% (52) | 94% (15) | 1.00 |
| Received Therapeutic Anticoagulation? | 39% (23) | 50% (8) | 0.57 |
| Received Hydroxychloroquine? | 46% (27) | 56% (9) | 0.58 |
| Received Convalescent Plasma? | 37% (22) | 50% (8) | 0.40 |
| Received Tocilizumab? | 7% (4) | 25% (4) | 0.06 |
| Day 28: | |||
| Ferritin | 480 (110) | 1200 (900) | 0.22 |
| D-dimer | 5.3 (6.7) | 6.8 (7.0) | 0.78 |
| Intubated | 36% (21) | 56% (9) | 0.16 |
| SOFA | 2 (2-11) | 8 (5-10) | 0.51 |
| Ordinal Scale | 2 (1-8) | 6.5 (3.5-7.5) | 0.16 |
| Received Glucocorticoids? | 47% (28) | 56% (9) | 0.58 |
| Received Remdesivir? | 12% (7) | 13% (2) | 1.00 |
| Received Vasopressors? | 32% (19) | 63% (10) | 0.04 |
| Received Antibiotics? | 69% (41) | 81% (13) | 0.53 |
| Received Therapeutic Anticoagulation? | 39% (23) | 69% (11) | 0.05 |
| Received Hydroxychloroquine? | 41% (24) | 44% (7) | 1.00 |
| Received Convalescent Plasma? | 27% (16) | 56% (9) | 0.04 |
| Received Tocilizumab? | 12% (7) | 25% (4) | 0.23 |
| At any point during hospitalization: | |||
| Received Glucocorticoids? | 73% (43) | 75% (12) | 1.00 |
| Received Remdesivir? | 14% (8) | 13% (2) | 1.00 |
| Received Pressors? | 44% (26) | 63% (10) | 0.26 |
| Received Antibiotics? | 100% (59) | 100% (16) | 1.00 |
| Received Anticoagulation? | 47% (28) | 81% (13) | 0.02 |
| Received Hydroxychloroquine? | 47% (28) | 56% (9) | 0.58 |
| Received Convalescent Plasma? | 62% (24) | 75% (9) | 0.50 |
| Received Tocilizumab? | 12% (7) | 25% (4) | 0.23 |