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. 2021 Jan 27;8(6):2004032. doi: 10.1002/advs.202004032

Figure 1.

Figure 1

CD146 expression is upregulated in adipose tissues from obese mice and humans. Western blot A) and RT‐qPCR B) showing CD146 levels in various mouse tissues. SVF, stromal vascular fraction. Western blot showing CD146 expression in white adipose tissue (WAT) C) and brown adipose tissue (BAT) D) from mice fed a normal diet (ND) or high‐fat diet (HFD) (n = 5 per group). Western blot showing CD146 expression in WAT E) and BAT F) from 12 week old (12w) ob/ob or control mice (n = 5 per group). Western blot showing CD146 expression in WAT G) and BAT H) from 4 week old (4w) or 12w ob/ob mice (n = 5 per group). I) Correlation between CD146 levels in WAT and the age of mice (n = 14). J) Correlation between CD146 levels in WAT and the body weight of mice (n = 14). K) Western blot showing CD146 expression in WAT from lean and obese humans. L) Correlation between CD146 levels in human WAT and body mass index (n = 36). Data represent the mean ± SD in (B) and the mean ± SEM in (C)–(H) and (K). P values were determined using Student's t‐tests (C–H,K).