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. 2021 Mar 9;22(5):2767. doi: 10.3390/ijms22052767

Figure 4.

Figure 4

Effects of the MG132 treatment on the BFA- and monensin-induced processing of CREB3 and CREB3L2 proteins in HEK293 cells. HEK293 cells were treated with BFA (0.5 µg/mL), monensin (1 µM), or vehicle, in the presence or absence of MG132 (10 µM), for 8 h. The expression of the indicated protein was detected as described in the Materials and Methods. Open and filled arrowheads indicate full-length mature and cleaved CREB3 and CREB3L2 proteins, respectively. Representative results of three independent cultures are shown.