Table 3.
Intra and postoperative outcome of procedures in the whole series and stratified according to period of recruitment.
| Variables | Whole Series | Period 1 (2004–2009) |
Period 2 (2010–2015) |
Period 3 (2015–2020) |
a vs. b | a vs. c | b vs. c | a vs. b vs. c | |
|---|---|---|---|---|---|---|---|---|---|
| 1212 | 293 | 353 | 566 | ||||||
| Operating time, median (range) | Minutes | 240 (150–640) | 300 (220–640) | 220 (180–510) | 250 (150–590) | NS | NS | NS | NS |
| Blood loss, median (range) | mL | 280 (100–1600) | 400 (100–1200) | 250 (100–1400) | 300 (100–1600) | 0.04 | NS | NS | NS |
| Pringle maneuvre, n (%) | 1053 (86.9) | 261 (89.1) | 309 (87.5) | 483 (85.3) | NS | NS | NS | NS | |
| Length of Pringle manouevre, median (range) | Minutes | 40 (15–135) | 30 (10–110) | 55 (10–120) | 45 (10–135) | 0.04 | 0.05 | NS | 0.05 |
| Intraoperative blood transfusion, n (%) | 96 (7.9) | 21 (7.2) | 34 (9.6) | 41 (7.2) | NS | NS | NS | NS | |
| Depth of liver margin, median (range) | mm | 5 (0–11) | 9 (0–22) | 8 (0–19) | 4 (0–11) | NS | 0.02 | 0.04 | 0.03 |
| Time to first flatus, median (range) | days | 3 (2–6) | 3 (2–6) | 3 (2–6) | 3 (2–6) | NS | NS | NS | NS |
| Return to diet, median (range) | days | 1 (0–6) | 1 (0–5) | 1 (0–6) | 1 (0–4) | NS | NS | NS | NS |
| Morbidity, n (%) | 295 (24.3) | 75 (25.6) | 90 (25.4) | 130 (22.9) | NS | NS | NS | NS | |
| Minor Morbidity (Dindo-Clavien I–II) | 201 (16.6) | 55 (18.7) | 56 (15.9) | 90 (15.9) | NS | NS | NS | NS | |
| Major Morbidity (Dindo-Clavien III–V) | 94 (7.8) | 20 (6.8) | 34 (9.6) | 40 (7.1) | NS | NS | NS | NS | |
| Mortality, n (%) | 19 (1.6) | 5 (1.7) | 7 (1.9) | 7 (1.2) | NS | NS | NS | NS | |
| Postoperative transfusions, n (%) | 178 (14.7) | 51 (17.4) | 63 (17.8) | 64 (11.3) | NS | 0.04 | 0.05 | 0.05 | |
| Total transfusions, n (%) | 223 (18.4) | 61 (20.8) | 72 (20.4) | 90 (15.9) | NS | NS | NS | NS | |
| Lenght of postoperative stay, median (range) | days | 5 (1–49) | 6 (1–38) | 5 (1–49) | 5 (1–43) | NS | NS | NS | NS |