Table 3.
Significantly differentially expressed genes related to microglia and innate immunity.
| Gene | Description | Fold Change (log2) | Adjusted p-Value < 0.05 |
|---|---|---|---|
| Gpr17 | G protein-coupled receptor 17 | −0.74 | 3.41 × 10−11 |
| Entpd1 | ectonucleoside triphosphate diphosphohydrolase 1 | −0.62 | 5.47 × 10−9 |
| Vsir | V-set immunoregulatory receptor | −0.52 | 2.14 × 10−6 |
| Lair1 | leukocyte-associated Ig-like receptor 1 | −0.45 | 7.76 × 10−6 |
| Csf1r | colony stimulating factor 1 receptor | −0.44 | 1.82 × 10−5 |
| Slc7a11 | solute carrier family 7 (cationic amino acid transporter, y + system), member 11 | −0.56 | 8.44 × 10−5 |
| Pik3cg | phosphatidylinositol−4,5-bisphosphate 3-kinase catalytic subunit gamma | −0.47 | 9.25 × 10−5 |
| Skap2 | src family associated phosphoprotein 2 | −0.35 | 3.80 × 10−4 |
| Lyz2 | lysozyme 2 | −0.55 | 9.26 × 10−4 |
| St6gal1 | beta galactoside alpha 2,6 sialyltransferase 1 | −0.35 | 1.65 × 10−4 |
| Il13ra1 | interleukin 13 receptor, alpha 1 | −0.33 | 6.58 × 10−4 |
| Fcgr3 | Fc receptor, IgG, low affinity III | −0.45 | 1.02 × 10−3 |
| Tlr7 | toll-like receptor 7 | −0.51 | 1.19 × 10−3 |
| Inpp5d | inositol polyphosphate-5-phosphatase D | −0.37 | 1.04 × 10−3 |
| Fyb | FYN binding protein | −0.47 | 1.63 × 10−3 |
| Lrrc3 | leucine rich repeat containing 3 | −0.38 | 1.43 × 10−3 |
| C3ar1 | complement component 3a receptor 1 | −0.41 | 2.80 × 10−3 |
| Cd300a | CD300A molecule | −0.50 | 4.39 × 10−3 |
| Ccl6 | chemokine (C-C motif) ligand 6 | −0.66 | 1.49 × 10−2 |
| Tnfsf8 | tumor necrosis factor (ligand) superfamily, member 8 | −0.58 | 4.39 × 10−3 |
| Itgb3 | integrin beta 3 | −0.36 | 1.46 × 10−2 |
| H2-Ob | histocompatibility 2, O region beta locus | −0.42 | 3.38 × 10−3 |
| Cxcr5 | chemokine (C-X-C motif) receptor 5 | 0.75 | 6.55 × 10−3 |