Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Mar 9;22(5):2774. doi: 10.3390/ijms22052774

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Results of the ApoToxGlo™ Triplex Assay. WM9 and WM164 cells were treated with 1 µM, 5 µM, 10 µM, and 20 µM of 5 for 4 h, 24 h, or 48 h (n = 6, mean ± sem). (A) Viability of the cells measured as relative fluorescence of control cells. (B) Cytotoxicity of 5 towards the cells measured as relative fluorescence of control cells. (C) Activity of caspases 3 and 7 indicative for apoptosis induction. Staurosporine (25 µM) served as positive control (apoptosis increase in WM9 cells after 24 h: 1193.9 % and after 48 h: 297.4%; in WM164 cells after 24 h: 989.1% and after 48 h: 362.6%).