Table 1.

Cellular cytotoxic activity of compounds 6–11, 15–20, 31–36, and 39–42.

Compound	IC50 a [µM]
6	115.38 ± 1.84
7	103.78 ± 1.16
8	4.33 ± 0.82
9	3.10 ± 0.42
10	8.02 ± 0.46
11	4.79 ± 1.36
15	67.78 ± 2.32
16	61.47 ± 2.33
17	9.68 ± 2.00
18	14.85 ± 0.86
19	14.30 ± 2.88
20	11.89 ± 0.48
31	53.09 ± 3.68
32	40.81 ± 1.67
33	4.77 ± 1.89
34	8.44 ± 1.70
35	8.65 ± 0.10
36	5.63 ± 0.16
39	10.63 ± 2.69
40	12.59 ± 0.68
41	10.38 ± 0.57
42	6.17 ± 1.21

^a Compound concentration required to; inhibit tumor cell growth by 50%; Mitonafide IC₅₀ < 1 [20]; Pinafide IC₅₀ = 1.23 ± 0.15 [20].