Oxaliplatin |
Polymeric nanoparticle |
CT26 |
Synergistic inhibitory effect of oxaliplatin and TA |
[49] |
Paclitaxel |
Nanoparticle |
MDA-MB-231 |
Reduced IC50 & increased cellular uptake of the drug compared to free drug |
[36] |
Gemcitabine, 5-Flurouracil &irinotecan |
Nanocomplex |
HPAF-II and PANC-1 |
Lower IC50 value& increased cellular uptake for the drugs |
[40] |
Gemcitabine, carboplatin &irinotecan |
Nanocomplex |
A549 and H1299 |
Enhanced decrease in IC50 from drug-loaded nanocomplex fabricated from TA and mice lung fluid |
[50] |
Doxorubicin hydrochloride |
Polymeric nanoparticle |
HeLa |
Similar inhibitory action of the nanoparticles compared to the free drug at the same concentration of 5 mg/mL |
[51] |
Nobelitin |
Coated nanoparticle |
H1299 |
Improved anticancer effect as well as good cytocompatibility at nobelitin concentration of 80 µg/ mL |
[52] |
Paclitaxel |
Nanocomplex |
A549 |
Lower IC50 values compared to both the pure drug and uncoated nanoparticles |
[53] |