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Levels of GAGs in HDFa (control) cells and MPS I and MPS II fibroblasts with and without treatment with 0.58 mg/L α-L-iduronidase (Aldurazyme, Ald) or 0.5 mg/L iduronate sulfatase (Elaprase, Ela) for 24 h. Mean values ± SD are presented, with asterisks and hashtags representing statistically significant (p < 0.05) differences relative to the HDFa control and untreated MPS, respectively.
