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. 2021 Mar 9;22(5):2766. doi: 10.3390/ijms22052766

Table 2.

Genes included into GO terms ‘Cellular component organization’ (GO:0016043) and ‘Cellular anatomical entity’ (GO:0110165) whose transcript levels were of up- (red) and down- (blue) regulated (at FDR < 0.1; p < 0.1) in at least nine (out of 11) types/subtypes of MPS relative to control cells (HDFa). Fold change (FC) levels are presented for individual transcripts. Noncolored boxes in the table indicate a lack of significance in the statistical analyses of differences between MPS and control cell lines.

GO Term/Gene log2FC of Transcripts whose Levels Were Changed in Most (at Least Nine) MPS Types vs. HDFa Line
Cellular Component organization I II IIIA IIIB IIIC IIID IVA IVB VI VII IX
MFAP5 3.50 5.49 6.14 5.00 4.51 3.75 3.93 4.11 4.61 4.20 4.40
PFN1 3.45 3.71 3.51 3.64 3.73 3.53 3.62 3.67 3.50 3.67 2.94
CAPG 2.73 2.98 4.71 1.98 4.27 2.75 4.17 4.14 3.82 4.28 4.55
POSTN 4.38 4.27 5.27 7.26 5.42 5.01 3.70 5.69 5.47 5.20 5.83
SIN3B −1.18 −1.55 −1.24 −1.47 −1.61 −1.92 −1.52 −1.69 −1.57 −1.67 −1.67
SAR1A −0.61 −0.55 −0.68 −0.61 −0.69 −0.31 −0.74 −0.64 −0.46 −0.46 −0.48
Cellular anatomical entity I II IIIA IIIB IIIC IIID IVA IVB VI VII IX
SH3BP5 1.37 1.34 1.76 1.38 1.08 0.63 0.86 1.02 1.29 1.24 0.96
POSTN 4.38 4.27 5.27 7.26 5.42 5.01 3.70 5.69 5.47 5.20 5.83
ARSA 1.06 1.13 1.13 1.09 0.14 1.48 1.00 0.80 0.92 1.36 1.11
TMEM38B −0.90 −0.87 −1.34 −1.06 −1.12 −1.44 −1.09 −0.86 −0.47 −1.18 −0.99
EMP1 −3.38 −3.43 −3.42 −3.67 −4.71 −3.11 −4.09 −3.74 −2.45 −1.79 −3.09
ABHD5 −1.69 −1.23 −1.74 −1.04 −1.08 −0.66 −1.22 −0.77 −0.99 −1.53 −1.06