Figure 1.
Case 1 (A), (B) H&E stained sections show diffuse medium-big sized cells with (C) thick nuclear membrane, rough chromatin, frequent apoptotic bodies and mitoses, forming a "star-sky phenomenon". Tumor cells are negative for CD3 (D), positive for CD20 (E), CD10 (F) and Bcl-6 (G), and are negative for c-MYC (H), has high proliferation rate by Ki‐67 (I), (A,×50; B,D-J,×200; C,×600). FISH showed negative for MYC rearrangements (J) and positive for centromeres lost (K) and 11q aberration (L).