Table 2.
Boswellia | Curcumin | Maritime Pine | |||||||
---|---|---|---|---|---|---|---|---|---|
Adverse Event | P | LD | HD | P | LD | HD | P | LD | HD |
Worsening fatigue | 1 | 1 | 1 | 1 | 1 | 1 | 1 | - | - |
Diarrhea | - | - | 1 | 1 | 1 | - | - | 1 | - |
Migraine | - | - | - | 1 | 1 | 1 | - | - | - |
Worsening gas | 1 | 1 | - | - | - | - | - | - | - |
Abdominal cramping | - | - | - | 1 | 1 | - | - | - | - |
Flushing of the face | - | - | - | 1 | 1 | - | - | - | - |
Dizziness | 1 | - | - | - | - | - | - | - | - |
Increased anxiety | - | - | 1 | - | - | - | - | - | - |
Worsening gas pain | - | - | - | - | - | 1 | - | - | - |
Nausea | - | - | - | - | - | 1 | - | - | - |
Itching | - | - | - | - | - | 1 | - | - | - |
Severe headache | - | - | - | - | - | 1 | - | - | - |
Worsening GERD | - | - | - | - | - | 1 | - | - | - |
Neck stiffness | - | - | - | - | - | - | - | 1 | - |
P = placebo, LD = lower dose, HD = higher dose, GERD = gastroesophageal reflux disease.