Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Mar 3;21(5):459. doi: 10.3892/etm.2021.9890

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Gao et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

CXCL12 overexpression reverses the inhibitory effect of miR-23 on inflammatory cytokine expression. (A) Transfection efficiency of siCXCL12. ELISAs were performed to assess the effects of CXCL12 knockdown on the secretory levels of (B) TNF-α, (C) IL-1β and (D) IL-8. (E) Transfection efficiency of pcDNA3.1-CXCL12. (F) The effects of miR-23 and CXCL12 co-overexpression on CXCL12 expression. ELISAs were performed to assess the effects of miR-23 and CXCL12 co-overexpression on the secretory levels of (G) TNF-α, (H) IL-1β and (I) IL-8. ^*P<0.05. CXCL12, chemokine C-X-C motif ligand 12; miR, microRNA; si, small interfering RNA; NC, negative control.