FIGURE 3.
IBA-1-positive microglia in the hippocampi of brains with different diseases. Sparse IBA-1-positive, rod-shaped microglia are present in the CA1 region in normal controls (CON, A), in Alzheimer disease (AD, B), in AD with hippocampal sclerosis (ADHS, C), and in FTLD-TDP type A without GRN mutations (FTLD-TDP type A, D), and are frequent in FTLD-TDP type A with GRN mutations (GRN, E and F). The rod-like microglia in FTLD-TDP type A with GRN mutations form end-to-end alignments (F). Bar: 50 µm.