HSS suppresses PA-induced endothelial cell inflammation. Human aortic endothelial cells were conditioned with 300 µM PA and subjected to HSS (12 dyn/cm2) for 20 h. Intercellular adhesion molecule-1 and monocyte chemoattractant protein-1 protein expression was determined by western blot analysis. Data are presented as the mean ± SEM from ≥ three independent experiments. *P<0.05 and #P<0.05. HSS, high shear stress; PA, palmitic acid; con, control; ICAM-1, intercellular adhesion molecule-1; MCP-1, monocyte chemoattractant protein-1.