Neuroprotective effects of FK18 against glutamate-induced apoptosis of SH-SY5Y cells tested by TUNEL assay. (A) Representative immunofluorescence images of TUNEL-positive (green) SH-SY5Y cells. Scale bar, 50 µm (magnification, x20). (B) Histogram indicating the percentages of TUNEL-positive cells relative to the total number of neurons following various treatments. The data are expressed as the mean ± SD. **P<0.01 vs. control group; ##P<0.01 vs. glutamate group. Control group, cells treated with normal saline; Glu, glutamate; bFGF, basic fibroblast factor.