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. 2021 Mar 3;21(5):460. doi: 10.3892/etm.2021.9891

Figure 1.

Figure 1

Clinical manifestations in lupus mice following 4-PBA and steroid treatment. (A) BWT increment from BALB/c (n=5) and murine lupus models that were treated with VEH (n=5), 4-PBA (n=5) and DEXA (n=5) for 4 weeks. (B) Comparisons of weight of the spleen and spleen to weight ratio among BALB/c murine lupus models treated with VEH, 4-PBA and DEXA. *P<0.05 vs. BALB/c mice; #P<0.05 vs. VEH-treated mice. Values are presented as the mean ± SEM of three independent experiments. 4-PBA, 4-phenylbutyric acid; BWT, body weight; DEXA, dexamethasone; VEH, vehicle.