Table 3.
Demographic features, disease activity and damage scores at last follow-up visit.
| Item | Asian (n = 134) | Black African/Caribbean (n = 69) | White Caucasian (n = 219) | P value |
|---|---|---|---|---|
| Follow-up in years | 4 [0–14.53] | 4 [0–13.86] | 4 [0–16.24] | 0.515 |
| Age at last visit in years | 16.8 [0.29–24.08] | 16.5 [4.55–27.02] | 16.9 [1.86–27.11] | 0.421 |
| Last follow-up total ACR score | 5 [5–7] | 5 [4–7] | 5 [4–6] | 0.250 |
| Maximum SLEDAI score | 12 [8.00–17.25] | 14 [8.00–20.00] | 14 [10.00–20.00] | 0.035 (A vs C = 0.031) |
| Max total pBILAG2004 score | 12 [6–18] | 11 [7–16] | 11 [6–16] | 0.551 |
| Maximum pBILAG2004 organ/system domain involvement throughout disease course | ||||
| Constitutional | 67 (50.0%) (41.5%, 58.5%) | 23 (33.3%) (22.2%, 44.5%) | 79 (36.1%) (29.7%, 42.4%) | 0.016 (C vs A = 0.008) |
| Mucocutaneous | 91 (67.9%) (60.0%, 75.8%) | 51 (73.9%) (63.6%, 84.3%) | 139 (63.4%) (57.1%, 69.9%) | 0.256 |
| Neuropsychiatric | 36 (26.9%) (19.4%, 34.4%) | 17 (24.6%) (14.5%, 34.8%) | 42 (19.2%) (14.0%, 24.4%) | 0.220 |
| Musculoskeletal | 63 (47.0%) (38.6%, 55.5%) | 37 (53.6%) (41.9%, 65.4%) | 117 (53.4%) (46.8%, 60.0%) | 0.467 |
| Cardiorespiratory | 21 (15.7%) (9.5%, 21.8%) | 19 (27.5%) (17.0%, 38.1%) | 52 (23.7%) (18.1%, 29.4%) | 0.092 |
| Gastrointestinal | 13 (9.7%) (4.7%, 14.7%) | 6 (8.7%) (2.1%, 15.3%) | 28 (12.8%) (8.4%, 17.2%) | 0.523 |
| Ophthalmic | 8 (6.0%) (2.0%, 10.0%) | 3 (4.4%) (−0.5%, 9.2%) | 6 (2.7%) (0.6%, 4.9%) | 0.322 |
| Renal | 90 (67.2%) (59.2%, 75.1%) | 51 (73.9%) (63.6%, 84.3%) | 130 (59.4%) (52.9%, 65.9%) | 0.062 |
| Hematological | 59 (44.0%) (35.6%, 52.4%) | 41 (59.4%) (47.8%, 71.0%) | 92 (42.0%) (35.5%, 48.6%) | 0.037 (B vs C = 0.01) |
Follow-up time and age at last visit were presented as median values with the minimum to maximum range. Total ACR, total pBILAG2004, SLEDAI are all presented as median values and interquartile ranges. For pBILAG2004 constituents, the number of patients with activity of A or B (deemed as signifying active organ domain involvement) was counted and presented as a percentage with 95% confidence intervals. Results of post-hoc pairwise comparison tests (Fisher’s Exact test) are indicated in curved brackets under the p value, indicating where the significant differences lie using the following codes: A = Asian, B = Black African/Caribbean, C = White Caucasian.