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. Author manuscript; available in PMC: 2021 Sep 1.
Published in final edited form as: Am J Manag Care. 2021 Mar 1;27(3):e80–e88. doi: 10.37765/ajmc.2021.88602

Table 3.

Choice of Initial Diabetes Medication in Traditional Medicare and Medicare Advantage*

Metformin Sulfonylureas (Short) Sulfonylureas (Long) Thiodolezinediones Insulin+ Other

TM MA Diff TM MA Diff TM MA Diff TM MA Diff TM MA Diff TM MA Diff
Overall 71.7% 72.8% −1.1% 6.9% 9.1% −2.2% 6.5% 6.2% 0.3% 1.6% 1.4% 0.2% 8.8% 8.6% 0.2% 9.9% 6.6% 3.3%

Region + + + + +

Northeast 70.3% 70.3% 0.0% 7.5% 8.8% −1.3% 6.2% 7.0% −0.8% 1.2% 1.1% 0.0% 7.7% 8.6% −0.9% 13.1% 9.7% 3.4%
Midwest 71.1% 72.7% −1.5% 7.3% 8.2% −0.9% 7.9% 7.0% 0.9% 1.5% 1.2% 0.3% 9.7% 10.0% −0.3% 7.6% 5.7% 2.0%
South 70.1% 72.3% −2.3% 6.1% 8.3% −2.2% 7.2% 7.1% 0.1% 1.7% 1.4% 0.3% 10.1% 8.6% 1.5% 9.7% 7.0% 2.7%
West 75.5% 75.4% 0.1% 7.5% 11.4% −3.9% 4.6% 3.5% 1.1% 1.9% 1.7% 0.2% 7.1% 7.7% −0.6% 9.5% 4.5% 5.0%

Plan Age + +

Established 71.5% 72.5% −1.0% 7.0% 8.9% −1.9% 6.4% 6.7% −0.3% 1.7% 1.4% 0.2% 8.7% 8.5% 0.2% 10.2% 6.4% 3.8%
New 71.8% 73.0% −1.2% 6.9% 9.3% −2.4% 6.5% 5.7% 0.8% 1.6% 1.4% 0.2% 8.9% 8.7% 0.2% 9.7% 6.8% 2.9%

Plan Size + +

Small 71.6% 72.7% −1.0% 7.2% 8.9% −1.7% 6.4% 6.0% 0.4% 1.6% 1.4% 0.2% 9.4% 9.1% 0.2% 9.3% 7.0% 2.3%
Large 71.7% 72.8% −1.1% 6.8% 9.2% −2.4% 6.5% 6.2% 0.3% 1.6% 1.4% 0.3% 8.6% 8.4% 0.2% 10.2% 6.5% 3.7%
*

TM estimates are weighted to match MA distributions by age category, sex, race/ethnicity categories, and geography. Differences between TM and MA are statistically significant at the p<.0001 level, except for (+), which was <.01.

Other includes GLP-1 agonists, DPP-4 inhibitors, SGLT-2 inhibitors, Meglitinides, and D-Phenylalanine Derivatives.