Table 2.
Comparative profile of male patients with MDD and control participants
| Variables | MDD1 | Control | P value |
|---|---|---|---|
| Number | 54 | 37 | – |
| Age (year)a | 42.4 ± 14.7 | 39.4 ± 7.0 | P = 0.187† |
| Body mass index (kg/m2)a | 24.2 ± 3.1 | 24.0 ± 3.5 | P = 0.661† |
| Smoker/non smoker | 13 / 41 | 5 / 32 | P = 0.214‡ |
| HbA1c (%)a4 | 5.4 ± 0.5 | 5.4 ± 0.8 | P = 0.970† |
| Cortisol (μg/dl)a | 12.1 ± 4.8 | 11.1 ± 3.0 | P = 0.191† |
| DHEAS (μg/dl)a2 | 227.9 ± 108.4 | 307.4 ± 131.2 | P = 0.002† |
| Cortisol / DHEAS ratioa | 0.07 ± 0.05 | 0.04 ± 0.02 | P = 0.001† |
| IGF1 (ng/ml)a3 | 171.5 ± 61.8 | 144.1 ± 39.2 | P = 0.011† |
| Testosterone (ng/ml)a | 5.0 ± 1.6 | 4.9 ± 1.6 | P = 0.709† |
| Estradiol (pg/ml)a | 22.4 ± 8.4 | 26.1 ± 8.5 | P = 0.040† |
aData are expressed as the mean ± standard deviation. †Unpaired t-test. ‡Chi-squared tests. Abbreviations: 1MDD Major depressive disorder, 2DHEAS Dehydroepiandrosterone and its sulfate, 3IGF1 Insulin-like growth factor 1, 4HbA1c Glycated hemoglobin