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. 2021 Mar 17;21:54. doi: 10.1186/s12874-021-01243-8

Table 2.

Model parameters for the screening numbers per week in a multivariable generalized mixed-effects model (Poisson family with logarithmic link function)

Predictor β coefficient* exp (β)* 95% interval for exp(β)* p value
Revision of inclusion criteria 0.186 1.204 (0.881–1.647) 0.243
Increase of travel expenses reimbursement 0.149 1.161 (0.859–1.570) 0.331
Investigator teleconferences 0.382 1.466 (1.018–2.112) 0.0398
Investigator meetings −0.084 0.919 (0.705–1.199) 0.534
Core partner site 0.379 1.460 (0.254–8.392) 0.671
Reaching 80% of site recruitment target −0.357 0.699 (0.542–0.903) < 0.001
Public holidays −0.763 0.466 (0.367–0.591) < 0.001
Week −0.006 0.994 (0.986–1.003) 0.202
Intercept −4.19 0.015 (0.005–0.045)

* adjusted values. No evidence for overdispersion was found (dispersion parameter: 1.0098, p = 0.3820 [19]). Only a shared fixed intercept is added when the site is inactive (β0 = − 4.19, exp.(β0) = 0.015, 95% CI [0.005–0.045]). Random intercepts α for active clinical sites ranged from 3.42 to 4.35