Table 5.

Residual water content quantified by coulometric KFT (n = 3, mean ± standard deviation).

System composition	Residual water content (%w/w)
Raw Sim	1.46 ± 0.28
0.1% w/v SD Sim (25% PR)	1.16 ± 0.54
0.1% w/v SD Sim (50% PR)	1.72 ± 0.59
0.5% w/v SD Sim (25% PR)	2.20 ± 0.19
0.5% w/v SD Sim (50% PR)	1.46 ± 0.03

KFT, karl fischer titration; PR, pump rate; SD, spray dried; Sim, simvastatin.