. Author manuscript; available in PMC: 2021 Mar 17.

Published in final edited form as: Clin Infect Dis. 2014 Dec 1;60(7):1075–1078. doi: 10.1093/cid/ciu956

Table 1.

Country-Specific and Pooled Rotavirus Vaccine Effectiveness by Season of Birth, Estimated From Multivariable Logistic Regression Models

Country^c	Aged <12 mo								Aged ≥12 mo
	Born in Rotavirus Season^a	Number Vaccinated				VE^b	[95%CI]	P Value	Number Vaccinated				VE^b	[95%CI]	P Value
	Born in Rotavirus Season^a	Cases	[%]	Controls	[%]	VE^b	[95%CI]	P Value	Cases	[%]	Controls	[%]	VE^b	[95%CI]	P Value
Bolivia	Yes	65/79	82	358/385	93	66	[30,83]	.26	48/64	75	367/398	92	76	[52,88]	.48
	No	13/19	68	145/156	93	84	[49,95]		81/106	76	478/505	95	82	[68,90]
El Salvador	Yes	33/47	70	117/132	89	70	[32,87]	.43	30/42	71	133/154	86	60	[8,82]	.91
	No	31/56	55	162/188	86	81	[62,90]		55/72	76	185/207	89	62	[23,81]
Guatemala	Yes	22/37	59	58/82	71	39	[−38,73]	.09	16/38	42	113/196	58	53	[4,77]	.74
	No	9/33	27	101/162	62	77	[48,90]		33/92	36	180/345	52	59	[33,75]
Nicaragua	Yes	23/28	82	230/252	91	57	[20, 81]	.88	40/45	89	275/307	90	10	[−143,67]	.17
	No	52/63	83	662/718	92	61	[−25, 85]		48/61	79	433/500	87	43	[−12,71]
United States	Yes	13/41	32	376/466	81	88	[76,94]	.17	76/339	22	947/1547	60	84	[77,89]	.71
	No	13/75	17	434/566	77	94	[88,97]		73/353	21	886/1465	61	85	[80,88]
Pooled	Yes	156/232	67	1139/1317	86	72	[61,80]	.01	210/528	40	1835/2602	71	76	[70, 81]	.54
	No	118/246	48	1504/1790	84	84	[78,88]		290/684	42	2162/3022	72	78	[73, 81]

Abbreviations: CI, confidence interval; VE, vaccine effectiveness.

Months included in rotavirus season for each country. Bolivia, Jul–Dec; El Salvador, Feb–June; Guatemala, Feb–May; Nicaragua, Jan–Apr; United States, Jan–Apr.

VE was adjusted for age (as a continuous variable, in months) and country of study.

Vaccine type included in each country. Bolivia, RV1; El Salvador, RV1; Guatemala, RV1 or RV5; Nicaragua, RV5; United States, RV1 or RV5.