Scheme 14:
Radiosynthesis and preclinical evaluation of 64 and 66. [a]: Biodistribution of 64 in the low activity organs of mice. [b]: PET-CT images of mice bearing LNCaP prostate cancer xenografts. Blocking was performed using non-radioactive CJ-042794. Biodistribution data and PET-CT images republished from references 96 and 97 with permission from Taylor & Francis (open access) and Elsevier, respectively.