Scheme 22:
Synthesis and preclinical evaluation of [18F]darapladib and [18F]FBnTP. [a]: Ex vivo tracer accumulations. 1: Macroscopic view. 2: 3D PET imaging view. 3: Corresponding orthoslice of planes a and b. [b]: Dynamic PET images of [18F]FBnTP in a female mouse, depicting myocardial uptake 1 min post-injection. Images republished from references 113 and 114 with permission from the ACS and John Wiley & Sons, respectively.