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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: Clin Transl Imaging. 2020 May 26;8(3):167–206. doi: 10.1007/s40336-020-00368-y

Scheme 32:

Scheme 32:

Radiosyntheses and preclinical evaluations of [18F]-SDM-8. Summed PET SUV images in NHP brain depicting baseline and LEV displacement (30 mg/kg) scans (Above) MRI and PET images in a human brain depicting uptake of 85 and [11C]UCB-J (Below) Images republished from references 109 and 146, with permission from the ACS and SNMMI, respectively.