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. 2021 Mar 24;12(3):115–143. doi: 10.5306/wjco.v12.i3.115

Table 3.

Tumor-node-metastasis American Joint Committee on Cancer 8th edition lung cancer

TNM AJCC 8th edition lung cancer
T: Primary tumour
Tx Not evaluable by imaging or malignant cells in sputum or bronchial lavage
T0 No evidence of primary tumour
Tis Carcinoma in situ
T1 ≤ 3 cm surrounded by lung or visceral pleura, or lobar bronchus
T1a (mi) Minimally invasive
T1a ≤ 1 cm
T1b > 1 cm to ≤ 2 cm
T1c > 2 cm to ≤ 3 cm
T2 > 3 cm to ≤ 5 cm, or involving main bronchus without affecting the carina, visceral pleura, or atelectasis or obstructive pneumonitis extending to the hilar region, affecting part or all of the lung
T2a > 3 cm to ≤ 4 cm
T2b > 4 cm to ≤ 5 cm
T3 > 5 cm to ≤ 7 cm, or tumour nodules in the same lobe, or invasion of the chest wall (parietal pleura), phrenic nerve, parietal pericardium
T4 > 7 cm, or nodules in a different ipsilateral lobe or invasion of the diaphragm, mediastinum, heart, great vessels, trachea, recurrent laryngeal nerve, esophagus, vertebral body, and carina
N: Regional lymph node involvement
Nx Not evaluable
N0 No node involvement
N1 Ipsilateral peribronchial and/or hilar and intrapulmonary nodes
N2 Ipsilateral mediastinal nodes and/or subcarinal
N3 Contralateral mediastinal or contralateral hilar nodes, or any scalene or supraclavicular nodes
M: Distant metastasis
M0 No metastasis
M1 Distant metastasis
M1a Nodules in contralateral lobe; pleural or pericardial or pleural or pericardial effusion
M1b Single extrathoracic metastasis (including non-regional lymph node)
M1c Multiple extrathoracic metastases

TNM: Tumor-node-metastasis; AJCC: American Joint Committee on Cancer.