Figure 5.

(a) String interactome map³⁹ of proteins belonging to the human NADH dehydrogenase [ubiquinone] complex identified from human cardiac tissue plus representative deconvoluted mass spectra of the protein complex subunits. (b) Mass spectra of voltage-dependent anion channel 1 (VDAC1) and tubulin alpha-1b (TUBA1B) along with a string interactome analysis of all voltage-dependent anion channels (VDAC) and tubulins identified from HEK293T cells. The interaction of VDAC and tubulin represents an ongoing area of neurodegeneration research and demonstrates the potential utility of this approach to probe endogenous interactions.⁵⁸