Table 4.
Comparison of the parameter decrease degree in subgroups with weight loss of more and less than 5% from baseline to the end of treatment
|
Parameter
|
Weight loss > 5% (n = 54)
|
Weight loss ≤ 5% (n = 120)
|
P
value
|
| ∆ALT, U/L | -21.1 (-45.0; -6.0) | -25.0 (-42.5; -6.0) | 0.683 |
| ∆ALT, % | -46 (-63; -18) | -43 (-54; -23) | 0.281 |
| ∆AST, U/L | -6.0 (-15.0; 1.6) | -5.0 (-18.0; 1.0) | 0.673 |
| ∆AST, % | 22 (-41; 0) | -17 (-42; 0) | 0.446 |
| ∆GGT, U/L | -5.0 (-17.0; 0) | -8.0 (-22.5; 0) | 0.492 |
| ∆GGT, % | -19 (-41; 0) | -32 (-50; 0) | 0.354 |
| ∆TC, mmol/L | -0.10 (-0.66; 0.30) | -0.10 (-0.57; 0.2) | 0.666 |
| ∆TG, mmol/L | -1.04 (-1.80; -0.23) | -0.70 (-1.33; -0.11) | 0.079 |
| ∆LDL, mmol/L | -0.20 (-0.7; 0.2) | -0.14 (-0.58; 0.3) | 0.401 |
| FLI | |||
| Initially | 88.3 ± 10.2 | 83.5 ± 10.3 | 0.002 |
| After 6 mo | 71.4 ± 19.6c | 72.8 ± 16.7c | 0.916 |
| ∆FLI | -14.6 (-21.8; -6.3) | -8.45 (-17.9; -2) | 0.003 |
c
P < 0.001. ∆ is the difference in indicators after 6 mo and at baseline. The minus sign indicates a decrease in the parameter by the end of the study.