Table 2.
Sensitivity, specificity, positive and negative predictive values and Kappa statistic of hospital data comorbidity as compared to study data. Conditions are ordered by prevalence
| Comorbidity | Sensitivity (95% CI) | Specificity (95% CI) | PPV (%) (95% CI) |
NPV (%) (95% CI) |
Kappa |
|---|---|---|---|---|---|
| Diabetes (n = 5461) | 97.7 (96.8–98.4) | 96.1 (95.4–96.7) | 90.4 (88.9–91.8) | 99.1 (98.7–99.4) | 0.91 |
| Ischaemic heart disease (n = 5450) | 82.6 (79.6–85.4) | 93.4 (92.7–94.1) | 82.9 (77.3–87.6) | 90.2 (89.4–91.0) | 0.68 |
| Malignancy (n = 5453) | 62.8 (58.3–67.2) | 97.7 (97.2–98.1) | 71.9 (67.3–76.2) | 96.5 (96.0–97.0) | 0.64 |
| Chronic lung disease (n = 5450) | 86.0 (82.3–89.2) | 90.4 (89.5–91.2) | 41.9 (38.6–45.4) | 98.8 (98.4–99.1) | 0.52 |
| Cerebrovascular disease (n = 5448) | 56.6 (51.2–61.9) | 96.7 (96.2–97.2) | 53.6 (48.3–58.9) | 97.1 (96.6–97.5) | 0.52 |
| Mental illness (n = 5451) | 55.1 (49.7–60.5) | 94.0 (93.3–94.7) | 38.1 (33.8–42.6) | 96.9 (96.4–97.5) | 0.41 |
| Peripheral vascular disease (n = 5452) | 67.2 (61.5–72.6) | 95.8 (95.2–96.3) | 47.7 (42.8–52.6) | 98.1 (97.7–98.5) | 0.53 |
| Heart failure (n = 5450) | 68.4 (61.3–75.0) | 91.4 (90.6–92.1) | 22.3 (18.9–25.9) | 98.8 (98.4–99.1) | 0.30 |
| Blood borne viruses (n = 5450) | 15.5 (10.2–22.2) | 100 (99.9–100) | 96.0 (79.6–99.9) | 97.6 (97.1–98.0) | 0.26 |
| Liver disease (n = 5452) | 44.2 (34.0–54.8) | 98.0 (97.6–98.4) | 28.4 (21.3–36.4) | 99.0 (98.7–99.3) | 0.33 |
| Heart valve replacement (n = 5448) | 92.6 (82.1–97.9) | 99.5 (99.3–99.7) | 65.8 (54.0–76.3) | 99.9 (99.8–100) | 0.77 |
| Permanent pacemaker (n = 5449) | 84.9 (72.4–93.3) | 98.6 (98.3–98.9) | 37.5 (28.8–46.8) | 99.8 (99.7–99.9) | 0.51 |
| Abdominal aortic aneurysm (n = 5447) | 29.5 (16.8–45.2) | 99.9 (99.7–99.9) | 61.9 (38.4–81.9) | 99.4 (99.2–99.6) | 0.40 |
| Dementia (n = 5453) | 44.4 (13.7–78.8) | 99.9 (99.7–99.9) | 36.4 (10.9–69.2) | 99.9 (99.8–100) | 0.40 |
Abbreviations: PPV Positive predictive value, NPV Negative predictive value