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PDCD4 was confirmed as a target gene of miR-503-5p. a. StarBase was used to predict the binding site of miR-503-5p and PDCD4. b. Dual-luciferase reporter gene assay was used to confirm the relationship between miR-503-5p and PDCD4. c-d. qRT-PCR and Western blot were used to detect the expression of PDCD4 in CRC cells after miR-503-5p was modulated. e. Pearson correlation analysis showed the negative relationship between PDCD4 and miR-503-5p in CRC tissues. ***P < 0.001
