Fig. 5.

Circ_0003266 inhibited malignant phenotypes of CRC cells by regulating miR-503-5p/PDCD4 axis. a. With transfection, SW480 cells were divided into four groups: NC group, circ_0003266 overexpression group, circ_0003266 overexpression + miR-503-5p overexpression group, and circ_0003266 overexpression + miR-503-5p overexpression + PDCD4 overexpression group, and Western blot assay was used to detect the expression of PDCD4 in SW480 cells. b. CCK8 assay was used to detect the proliferation of SW480 cells after the transfection. c-d. Transwell assay was used to detect the migration and invasion of SW480 cells after the transfection. e. Flow cytometry was used to detect the apoptosis rate of SW480 cells after the transfection. **P < 0.01 and ***P < 0.001