Figure 3.
(A) Schematic of the Confetti approach for fluorescent labelling of immune cells. 63 Inducible Cre‐mediated recombination of the Confetti locus leads to differential labelling of cells with GFP, YFP, RFP or CFP (upper panel). This experimental approach can, for example, be used for analysis of local replication, death and migration rates of immune cells as observed upon exposure to a microbial trigger (lower panel). (B) Schematic of a neutral genetic barcoding approach of T cells. Genetic barcodes are introduced ex vivo by retroviruses. The barcoded cells can be transplanted into recipient hosts (upper panel) and employed to study cell survival, death, replication, differentiation and migration (lower panel). 69