Figure 2.

MRI acquisition and analysis. (A) T2-weighted FSE and (B) T1-weighted GRE images were collected for each animal at each time point. (C) FSE and GRE images were overlaid to determine areas of injury, edema, and/or tissue consolidation identified in FSE images that were not correlated with blood vessels or organs identified in GRE images. (D) Regions of interest (ROI) in FSE images were manually selected. The volume (mm3) of lung injury (shown in red) was then calculated for each animal. Representative images from one animal acquired 3 d post NM exposure are shown.