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. 2021 Mar 5;16(1):198–209. doi: 10.1515/biol-2021-0013

Figure 6.

Figure 6

si-MMP-2 inhibited the cell proliferation, invasion, and EMT but promoted the cell apoptosis rate in vitro. (a) MMP-2 protein expression in GI-LI-N and SK-N-SH cells with si-MMP-2 was measured by western blot assay and normalized to GAPDH. (b and c) Cell proliferation of the cells with si-MMP-2 or si-NC was detected by CCK-8 assay at 450 nm. (d) Flow cytometry was used to analyze the cell apoptosis rate in cells with si-MMP-2 or si-NC. (e) Cell invasion in si-MMP-2 or si-NC groups was confirmed by transwell assay. (f) Western blot assay was adopted to visualize the E-cadherin, N-cadherin, and vimentin protein expression of cells with si-MMP-2 or si-NC. *P < 0.05.