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Phenotypes that are expected to show full (FR), partial, or no rescue (NR) when paternal Ube3a is unsilenced at different developmental time periods in AS model mice. Expectations based on data in (Meng et al., 2015; Silva-Santos et al., 2015).
| Developmental time period | ||||
|---|---|---|---|---|
| Phenotype | Embryonic | P0 | P21 | Adult |
| Learning/Memory | FR | FR | FR | FR |
| Rotarod | FR | FR | Partial | NR |
| Open field | FR | FR | NR | NR |
| Marble burying | FR | NR | NR | NR |
| Nest building | FR | NR | NR | NR |
| Forced swim | FR | NR | NR | NR |
