Table 3.

Drug-Liking at This Moment: Individual Maximum Values, Differences Between Drug and Placebo (PD Population, n = 34)

Comparison	Median differencea	IQR	P  b
Silexan 80 mg vs placebo	0.0	(−1) – 10	.2600
Silexan 640 mg vs placebo	0.0	(−2) – 14	.2809
Lorazepam 2 mg vs placebo	19.5	11 – 31	<.0001
Lorazepam 4 mg vs placebo	24.5	15 – 36	<.0001
Silexan 80 mg vs lorazepam 2 mg	−18.0	(−29) – (−7)	<.0001
Silexan 640 mg vs lorazepam 2 mg	−12.0	(−24) – 0	.0005
Silexan 80 mg vs lorazepam 4 mg	−23.0	(−34) – (−15)	<.0001
Silexan 640 mg vs lorazepam 4 mg	−20.5	(−27) – (−1)	<.0001

Abbreviations: IQR, interquartile range (25^th–75th percentile); PD, pharmacodynamic.

^aPositive values denote greater liking for the drug named first.

^bWilcoxon signed rank test in intraindividual differences.