Table 1:

CNS applications of advanced MR imaging techniques

Technique	Application
DTI and fiber tractography12,13	Biopsy guidance
	Determination of functionally eloquent tracts and surgical plan
PWI14–24
DSC	Differential diagnosis: tumor vs nontumoral lesions, primary vs metastatic lesions, tumor grading, tumor complications, treatment response, pseudoprogression
DCE	Differential diagnosis: tumor vs nontumoral tissue, tumor grading, treatment response, pseudoprogression
DWI25,26	Differential diagnosis: tumor vs nontumoral lesions, tumor grading, treatment response
ADC27,28	Glioma grading, differentiation of high cellularity lymphoma
MRS29–33	Differential diagnosis: tumor vs nontumoral lesions, primary vs metastatic lesions, treatment response
Blood oxygen level–dependent imaging34	Neuronal activity, surgical guidance
Nuclear medicine, PET35	Biopsy guidance, treatment response, differential diagnosis: tumor recurrence vs radionecrosis
Volumetric imaging36	Not widely available and implementable