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. 2021 Mar 17;7(12):eabf7412. doi: 10.1126/sciadv.abf7412

Fig. 2. Gene expression of promyogenic line diverges from the blunted lines.

Fig. 2

(A) Venn diagram summarizes overlap in number of differentially expressed genes (DEGs) across all time points in the three cell lines (TL, yellow; SCVI15, red; or LEPCC3, blue), with total number of DEGs listed below. (B) Graph shows number of DEGs (y axis) with respect to time (x axis) and cell line (TL, blue; SCVI, green; LEPCC3, red). Each pair of bars represents up-regulated transcripts on the left and down-regulated transcripts on the right. The top-most section of each bar represents the number of noncoding up-regulated (Up) and down-regulated (Dn) transcripts. (C) Hierarchical clustering with respect to DEGs of all time points from all cell lines [LEPCC3 (L*), magenta; SCVI15 (S), green; TL (T), blue]. Darker color represents increasing time of differentiation. Asterisk marks the promyogenic line.