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. 2021 Mar 17;15(3):e0009244. doi: 10.1371/journal.pntd.0009244

Table 3. Summary estimates of diagnostic accuracy for S. japonicum (stool examination as a reference standard).

ELISA IHA PCR
Estimate 95% CI Estimate 95% CI Estimate 95% CI
Sensitivity 0.93 0.84 0.98 0.97 0.90 0.99 0.89 0.71 0.96
Specificity 0.40 0.29 0.53 0.66 0.58 0.73 0.49 0.29 0.69
Positive Likelihood Ratio 1.6 1.3 1.8 2.8 2.2 3.6 1.7 1.3 2.4
Negative Likelihood Ratio 0.17 0.08 0.35 0.05 0.01 0.17 0.23 0.11 0.49
Diagnostic Odds Ratio 9.0 4.0 20 60 15 242 8.0 4.0 16
Positive Predictive Value 0.43 0.40 0.45 0.30 0.27 0.32 0.35 0.33 0.38
Negative Predictive Value 0.92 0.91 0.94 0.96 0.94 0.97 0.91 0.89 0.93

Note: CI-Confidence interval; ELISA-Enzyme-Linked immuno sorbent assay; IHA-Indirect haemagglutination assay; PCR-Polymerase chain reaction.