Table 3. Summary estimates of diagnostic accuracy for S. japonicum (stool examination as a reference standard).
ELISA | IHA | PCR | |||||||
---|---|---|---|---|---|---|---|---|---|
Estimate | 95% CI | Estimate | 95% CI | Estimate | 95% CI | ||||
Sensitivity | 0.93 | 0.84 | 0.98 | 0.97 | 0.90 | 0.99 | 0.89 | 0.71 | 0.96 |
Specificity | 0.40 | 0.29 | 0.53 | 0.66 | 0.58 | 0.73 | 0.49 | 0.29 | 0.69 |
Positive Likelihood Ratio | 1.6 | 1.3 | 1.8 | 2.8 | 2.2 | 3.6 | 1.7 | 1.3 | 2.4 |
Negative Likelihood Ratio | 0.17 | 0.08 | 0.35 | 0.05 | 0.01 | 0.17 | 0.23 | 0.11 | 0.49 |
Diagnostic Odds Ratio | 9.0 | 4.0 | 20 | 60 | 15 | 242 | 8.0 | 4.0 | 16 |
Positive Predictive Value | 0.43 | 0.40 | 0.45 | 0.30 | 0.27 | 0.32 | 0.35 | 0.33 | 0.38 |
Negative Predictive Value | 0.92 | 0.91 | 0.94 | 0.96 | 0.94 | 0.97 | 0.91 | 0.89 | 0.93 |
Note: CI-Confidence interval; ELISA-Enzyme-Linked immuno sorbent assay; IHA-Indirect haemagglutination assay; PCR-Polymerase chain reaction.