Table 1.
Summary of published HIN domain structures of PYHIN family proteins
| Protein | Positions of Class A HIN | Positions of Class B HIN | Positions of Class C HIN | dsDNA | Resolution (Å) | PDB entry | Reference |
|---|---|---|---|---|---|---|---|
| hAIM2 | 144–343 | 20 mer | 2.55 | 3RN2* | (29) | ||
| hAIM2 | 144–343 | 19 mer | 2.50 | 3RN5 | (29) | ||
| mAIM2 | 158–349 | 13 mer | 2.22 | 4JBM* | (30) | ||
| IFI16 | 192–393 | 2.00 | 2OQ0* | (55) | |||
| IFI16 | 192–393 | 12 mer | 2.54 | 4QGU* | (36) | ||
| IFI16 | 571–766 | 2.35 | 3B6Y* | (55) | |||
| IFI16 | 571–766 | 1.80 | 3RLO | (29) | |||
| IFI16 | 571–766 | 2.25 | 3RLN | (29) | |||
| IFI16 | 571–766 | 16 mer | 2.50 | 3RNU* | (29) | ||
| p202 | 46–242 | 2.69 | 4JBJ* | (30) | |||
| p202 | 46–243 | 2.23 | 4L5Q | (35) | |||
| p202 | 46–242 | 14 mer | 2.96 | 4JBK | (30) | ||
| p202 | 46–243 | 20 mer | 1.87 | 4L5R* | (35) | ||
| p202 | 46–243 | 12 mer | 2.94 | 4L5S | (35) | ||
| p202 | 53–245 | 20 mer | 2.00 | 4LNQ | (34) | ||
| p202 | 244–445 | 3.40 | 4L5T* | (35) | |||
| p204 | 211–415 | 1.94 | 6OE9 | (56) | |||
hAIM2: human AIM2.
mAIM2: mouse AIM2.
*Used to compare with p204 HIN structures.