Table 2.
Quantitative measurement of retinal parameters.
| Study | Location | Eyes (n) | Age (year) | Gestational age (week) | Measured areas | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Preeclampsia | Normal pregnancy | Nonpregnancy | Preeclampsia | Normal pregnancy | Nonpregnancy | ||||||
| Atas, 2014 | Turkey | 27 | 25 | 26 | 30.81 ± 6.46 | 27.76 ± 5.21 | 29 ± 7.1 | 38.35 ± 3.1 | RNFL (μm) Mean ± SD |
Preeclampsia | 102.45 ± 8.69 |
| Normal pregnancy | 104.77 ± 10.64 | ||||||||||
| Nonpregnancy | 97.62 ± 12.27 | ||||||||||
|
| |||||||||||
| Neudorfer, 2014 | Israel | 20 | — | — | NA | — | — | NA | RNFL (mm) | Mild preeclampsia | 91 |
| Severe preeclampsia | 98 | ||||||||||
|
| |||||||||||
| Arab, 2018 | Iran | 210 (70/140) | 88 | — | 28.6 ± 6.2 | 26.2 ± 5.7 | — | 36.5 ± 2.7 | RNFL (μm) Mean ± SD |
Mild preeclampsia | 104 ± 10 |
| Severe preeclampsia | 104 ± 23 | ||||||||||
| Normal pregnancy | 106 ± 9 | ||||||||||
|
| |||||||||||
| Asal, 2019 | Turkey | 30 | 30 | — | 28.1 ± 6.5 | 26.6 ± 5.9 | — | 35.7 ± 2.9 | RNFL (μm) Mean ± SD |
Preeclampsia | 101.7 ± 12.8 |
| Normal pregnancy | 103.3 ± 11.6 | ||||||||||
|
| |||||||||||
| Ciloglu, 2019 | Turkey | 55 | 43 | 38 | 30.05 ± 5.75 | 31.4 ± 5.15 | 33.37 ± 7.96 | 35.89 ± 2.88 | RNFL (μm) Mean ± SD |
Preeclampsia | 103.73 ± 11.61 |
| Normal pregnancy | 104.85 ± 11.95 | ||||||||||
| Nonpregnancy | 97.82 ± 9.78 | ||||||||||
|
| |||||||||||
| Garg, 2014 | United States | 15 | — | 19 | 32.7 ± 7.6 | — | 27.9 ± 5.1 | 32.5 ± 4.9 | Retinal macular volume (mm3) | Preeclampsia | 9.0 ± 0.4 |
| Normal pregnancy | 8.7 ± 0.5 | ||||||||||
| Nonpregnancy | 8.8 ± 0.4 | ||||||||||
|
| |||||||||||
| Kim, 2015 | Korea | 7 | 14 | 21 | 31.86 ± 4.06 | 31.43 ± 2.88 | 30.43 ± 4.15 | 34.57 ± 16.81 | Central subfield retinal thickness, CSRT (μm) | Preeclampsia | 262.29 ± 12.39 |
| Normal pregnancy | 258.93 ± 18.97 | ||||||||||
| Nonpregnancy | 264.48 ± 18.73 | ||||||||||
|
| |||||||||||
| Kolenko, 2019 | Khabarovsk | 42 | 20 | — | NA | NA | NA | NA | Macular retinal volume, MRV (mm) | Mild preeclampsia | 6.8 ± 0.4 |
| Average preeclampsia | 7.4 ± 0.5 | ||||||||||
| Severe preeclampsia | 8.5 ± 0.7 | ||||||||||
NA, not available.