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. 2021 Jan 18;2021:5472605. doi: 10.1155/2021/5472605

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Copyright © 2021 Manman Zhao et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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ICH triggered autophagy activation in the nonhemorrhagic hippocampus. (a) Representative images of electron microscopy in the ipsilateral hippocampus after ICH. The asterisk symbol indicated phagophore, the hash symbol presented typical autophagosomes, and the arrow showed the formation of autolysosomes. Bar, 1 μm. (b) The colocalization of LC3 (red) in the neuron (green) of the hippocampal CA1 region after ICH. Bar, 30 μm. (c, d) Representative bands and quantitative analysis of Beclin-1 and p62 in the ipsilateral hippocampus. ^∗P < 0.05 compared with the Sham group; ^#P < 0.05 compared with the ICH group.