Table 1.

Participant Characteristics

Measure	Mean (SD)
Age (yr)	50 (9)
Height (cm)	178 (6)
Weight (kg)	105 (12)
BMI (kg/m2)	33 (3)
Fat mass (kg)	33 (6.4)
Lean mass (kg)	67 (6.2)
% Body Fat	31.6 (4)
HbA1c (%)	5.7 (0.5)
HOMA2-%B	139.4 (56)
HOMA2-%S	46 (16)
Fasting glucose (mmol/L)	5.9 (0.7)
2-hr OGTT glucose (mmol/L)	9.1 (0.5)
Fasting Insulin (pmol/L)	131 (57)
Triglycerides (mmol/L)	1.9 (0.27)
Total cholesterol (mmol/l)	4.8 (0.83)
HDL-cholesterol (mmol/l)	0.99 (0.13)
LDL-cholesterol (mmol/l)	3.0 (0.75)
% Time Sedentary	69 (19.2)
% Time Light Activity	21 (11.4)
% Time Moderate Activity	10 (9.5)
% Time Vigorous Activity	0 (0)

Values are presented as mean ± SEM. % of time spent in each activity were derived from accelerometry data (see ESM). WB = whole body. 2-hr OGTT is plasma glucose at 2-hours after a 75-gram oral glucose challenge. HOMA2 calculated using the HOMA2 calculator accessed from (http://www.dtu.oc.ac.uk) (20).