A) Serum IL-1β assessed by ELISA at 15 (E = early) and 30 days (L = late). One-way ANOVA F(2, 12) = 15.9, p<0.0004, n = 5/group. Multiple comparisons: Saline vs E p = 0.91, Saline vs L p = 0.0005 and E vs L p = 0.0033. B) mRNA levels of Il1b in the liver at 15 and 30 days. One-way ANOVA F(2, 16) = 24.8, p<0.0001, n = 5–8/group. Multiple comparisons: Saline vs E p = 0.84, Saline vs L p<0.0001 and E vs L p = 0.0002.