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. 2020 Jul 13;478(2):319–326. doi: 10.1007/s00428-020-02889-3

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© The Author(s) 2020

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Fig. 3 — A representative case of undifferentiated carcinoma of the pancreas is shown. a Hematoxylin-eosin staining reveals an undifferentiated carcinoma with atypical cells lacking any glandular organization. On the left, there is a thin band of normal pancreatic parenchyma (original magnification: × 20). b Snai2 is expressed by most of neoplastic cells and not expressed by normal pancreatic parenchyma (original magnification: × 20). c Twist1 is totally negative in neoplastic and normal tissues (original magnification: × 20); d E-cadherin expression is lost by neoplastic cells, with the normal pancreatic parenchyma as an internal positive control (original magnification: × 20)