Table 1.

IL-6, TNF-α and DETA/NO upregulate cGMP levels in rat brain striatum

	cGMP (pg/mg protein)
	15 min	30 min
Control	0.80 ± 0.06	0.66 ± 0.02
IL-6 (50 ng)	2.86 ± 0.28**	2.53 ± 0.21**
DETA/NO (1 mM)	2.63 ± 0.25**	2.73 ± 0.29**
TNF-α (50 ng)	3.80 ± 0.30***	2.63 ± 0.23**

Values represent the means ± SEM. ** p < 0.01, *** p < 0.001 vs control (0 h sham-operated animals) (ANOVA and Bonferroni post-test)