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. 2021 Mar 17;11:6113. doi: 10.1038/s41598-021-85460-7

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Effect of early socialization and environmental enrichment on transepithelial ion transport paracellular permeability to fluorescent tracers at day 3 post weaning. (a) Basal colonic I_sc, (b) Basal colonic PD, (c) Basal colonic TEER, (d) FD4 flux, (e) FD4 slope and (f) TEER at 120 min.