Table 1.

Mean DCrt results obtained for the 51 genes that could be quantitatively determined, both during lactation and after weaning for CTR and ENR piglets. Details for the different genes can be found in Supplementary Table S4. (BF: Barrier function related genes/EH: Enzymes/Hormones related genes/IR: Immune system related genes/NT: Nutrient Transport related genes/ST: Stress related gene).

Function	Gene	LACT				WEAN
		CTR	ENR	SEM	P-value	CTR	ENR	SEM	P-value
BF	TFF3	3.69	3.74	0.151	0.9254	3.17	3.21	0.197	0.9799
BF	OCLN	7.89	7.67	0.125	0.7494	6.97	7.13	0.075	0.8255
BF	ZO1	4.28	4.11	0.132	0.8836	4.06	3.83	0.090	0.7439
BF	CLDN1	17.51	16.07	0.550	0.7494	16.48	15.56	0.397	0.7466
BF	CLDN4	15.63	15.28	0.188	0.7494	14.64	14.83	0.204	0.8644
BF	CLDN15	9.00	8.58	0.234	0.7494	9.49	9.36	0.112	0.8255
BF	MUC2	5.37	5.61	0.211	0.8836	4.87	4.64	0.199	0.8255
BF	MUC13	2.43	2.30	0.294	0.9194	1.22	1.07	0.092	0.8255
EH	SI	3.07	2.74	0.323	0.8836	1.40	1.54	0.199	0.9888
EH	DAO1	2.95	2.74	0.373	0.9491	2.37	2.54	0.138	0.8255
EH	HNMT	5.49	5.16	0.157	0.9062	4.63	4.64	0.099	0.9799
EH	ANPEP	1.43	0.48	0.378	0.7788	0.37	0.33	0.120	0.9799
EH	IDO1	9.19	8.65	0.443	0.9062	8.21	7.35	0.318	0.7439
EH	GCG	4.95	4.17	0.220	0.6220	4.19	4.01	0.122	0.8255
EH	CCK	7.36	7.36	0.165	0.9925	9.15	9.77	0.303	0.8255
EH	IGF1R	6.39	6.15	0.171	0.8836	7.93	7.11	0.199	0.7439
EH	PYY	7.16	6.61	0.233	0.7494	6.83	7.04	0.194	0.8255
EH	GPX2	4.88	5.21	0.327	0.8836	5.65	4.45	0.395	0.7439
EH	SOD2.m	4.62	4.63	0.170	0.9925	5.00	4.49	0.133	0.7439
EH	ALPI	2.28	1.17	0.545	0.9194	0.54	1.23	0.196	0.7439
IR	TLR2	13.57	13.15	0.234	0.7494	13.94	11.69	0.391	0.0315
IR	TLR4	7.63	7.55	0.179	0.9254	8.07	7.22	0.291	0.7439
IR	IL1B	10.79	9.57	0.354	0.6220	9.61	9.00	0.342	0.8255
IR	IL6	13.62	12.70	0.373	0.7494	13.20	12.67	0.270	0.8255
IR	IL10	10.24	9.91	0.171	0.7494	9.55	9.58	0.173	0.9799
IR	IL17A	17.86	17.43	0.469	0.8836	16.58	16.67	0.470	0.9799
IR	IL22	12.57	12.10	0.583	0.8836	11.84	11.91	0.324	0.9799
IR	IFN-γ	9.86	9.05	0.448	0.7494	9.13	8.85	0.261	0.8255
IR	TNF-α	9.62	8.97	0.231	0.7494	9.08	8.56	0.186	0.7439
IR	TGF-β1	5.29	5.33	0.101	0.9254	5.22	5.01	0.148	0.8255
IR	CCL20	5.88	4.77	0.561	0.7494	4.64	4.79	0.392	0.9799
IR	CXCL2	10.23	9.10	0.373	0.7494	10.15	9.65	0.309	0.8255
IR	IFNGR1	4.78	4.58	0.214	0.8813	3.29	3.36	0.094	0.9115
IR	HSP27	3.35	2.83	0.228	0.7494	2.97	3.35	0.128	0.7439
IR	HSP70	3.51	3.24	0.186	0.8698	3.24	3.24	0.075	0.9964
IR	REG3G	6.38	6.58	0.502	0.9254	7.02	3.74	0.970	0.7439
IR	PPARGC1α	7.28	7.28	0.147	0.9925	7.90	8.09	0.159	0.8255
IR	FAXDC2	6.23	4.52	0.490	0.6825	4.05	4.76	0.298	0.7164
IR	GBP1	3.19	2.59	0.329	0.8797	2.77	2.63	0.131	0.8255
IR	IL8	4.67	4.39	0.245	0.8836	4.78	4.53	0.200	0.8255
NT	SLC5A1	2.38	1.97	0.530	0.9491	1.35	1.46	0.252	0.8225
NT	SLC16A1	6.44	6.78	0.196	0.9062	7.86	7.65	0.166	0.8255
NT	SLC7A8	8.03	5.84	0.621	0.6220	7.73	7.18	0.432	0.8255
NT	SLC15A1	5.18	4.00	0.463	0.7788	3.14	3.80	0.264	0.7907
NT	SLC13A1	7.55	5.07	0.576	0.6825	4.15	4.62	0.181	0.7798
NT	SLC11A2	6.63	6.58	0.092	0.9254	6.99	6.84	0.117	0.8255
NT	SLC30A1	5.07	4.48	0.171	0.7326	3.59	3.77	0.136	0.8255
NT	SLC39A4	4.54	4.70	0.202	0.8836	5.91	6.29	0.152	0.7439
ST	CRHR1	15.00	15.68	0.362	0.7494	15.20	15.14	0.333	0.9799
ST	NR3C1-Grα	6.59	6.11	0.123	0.7326	6.51	6.41	0.089	0.8255
ST	HSD11B1	8.56	8.98	0.184	0.8486	10.24	9.42	0.270	0.7439